Topic: Early Termination

The Next 25 Years in Clinical Research: Learning to Learn Faster

Missed Opportunities to Advance Clinical Research 605 BCE In Nebuchadnezzar’s court, Daniel and friends conducted a controlled trial comparing the effects of a meat-and-wine diet to Daniel’s preferred fare of lentils and water. King James Bible, Daniel Chapter 1 560-547 BCE Croesus, King of the Lydians, conducted a blinded controlled test of the accuracy of… Read more »

Amnesty for Reluctant Early Stoppers in Clinical Development

In the C-Suite, virtually all biopharma companies insist on failing unsuccessful candidates faster and reallocating resources to more promising molecules. This is only rational. But the industry has a dirty little secret. This isn’t the kind of secret that stays within the confines of the C-Suite. It’s the kind that never bubbles up that high…. Read more »

Faster to Market, Faster to Fail

The team at Health Decisions enjoys nothing more than helping a sponsor bring a successful product to market months or years ahead of schedule. Through a combination of adaptive design and adaptive operations, we have succeeded in accelerating market entry for many products, sometimes by more than two years, as in the case of one… Read more »