Tagged: actionable information

Reflections on James Lind’s Scurvy Trial, Pharmacoeconomics, Sovaldi and Other Hot Topics in Clinical Research

Yesterday we celebrated May 20 as International Clinical Trials Day because James Lind started his famous trial of scurvy treatments on this date in 1747. Lind’s study remains noteworthy as perhaps the first controlled study that demonstrated the efficacy of a treatment that is still known to be effective. Lind conducted the multiarm trial aboard… Read more »

Biopharma’s R&D Productivity Problem Resurfaces as We Enter 2014

While FDA approvals of truly new drugs and biologics soared to 39 in 2012, the story as we enter 2014 shows a striking reversion to lower productivity levels that have long plagued the industry. The number of FDA approvals dropped to 27 in 2013. Big Pharma can take credit for only 14 of the approved… Read more »

Actionable Information: What You Don’t Know about Your Trial but Should

I’ve repeatedly emphasized the importance of timely, actionable information in increasing the efficiency of clinical trials. When I do talks, I often discuss this in some detail but readers sometimes ask exactly what sorts of information I’m talking about.  So let’s look at some key performance metrics for site performance and then move on to… Read more »